Synthra Product Range

Synthra FDGtwo

Production of FDG, a wide variety of Fluorine-18 and fluorinated compounds

[18F] compound

[18F]-Radiotracer Target Application
FDG Glucose metabolism Tumour diagnostic






Synthra RNplus

Production of [18F]F-DOPA, [18F]FDG, [18F]FLT, [18F]FHBG, [18F]FDDNP, [18F]MISO, [18F]FAZA and [18F] Fluoro choline

Examples for [18F] compounds

[18F]-Radiotracer
Target
Application
FLT DNA proliferation Tumour cell proliferation
FDDNP ß-amoloid protein Alzheimer disease
Flumazenil Benzodiacepine receptor Epileptic foci
FHBG Gene expression Cancer gene therapies
Fluorocholine Choline kinase Brain tumours, prostate,
lung and esophageal cancer
F-Mizo Hypoxic cell marker Head and neck cancer
F-Dopa D2 dopamine receptors Neurodegenerative diseases
FDG Glucose metabolism Tumour diagnostic





Synthra F-Dopa

Production of 6-[18F]fluoro-L-Dopa and a variety of Fluorine-18
Examples for electrophilic [18F] compounds

[18F]-Radiotracer
Target
Application
F-Dopa D2 dopamine receptors Neurodegenerative diseases





Synthra Mel

Production of [11C]-Methyl Iodide or optionally [11C]-Methyl Triflate
[11C] Compound

[11C]-Radiotracer
Target
Application
[11C]-CH3I GPextent [11C]-labelling





Synthra Melplus

Production of Carbon-11 labelled compounds based on C-11 Methyl Iodide or optional C-11 Methyl Triflate synthesis
Examples for electrophilic [11C] compounds

[11C]-Radiotracer
Target
Application
Raclopride D2 dopamine receptors Neuropsychiatric disorders

DASP

D2 dopamine receptors

Neuropsychiatric disorders

Flumazenil

Benzodiacepine receptor

Neurodegenerative diseases

Methionine

Amino acid transporter

Brain, head and neck, lung and breast cancer, lymphomas

Choline

Choline kinase

Brain tumours, prostate, lung and esophageal cancer

Thymidine

Thymidine kinase-1

Tumour proliferation

Palmitate

Myocardinal tissue fatty acid metabolism

Heart diseases






Synthra GPextent

Production of 11C labelled tracer by Methyl Iodide or Methyl Triflate gas phase synthesis
Examples for electrophilic [11C] compounds

[11C]-Radiotracer
Target
Application
Raclopride D2 dopamine receptors Neuropsychiatric disorders

DASP

D2 dopamine receptors

Neuropsychiatric disorders

Flumazenil

Benzodiacepine receptor

Neurodegenerative diseases

Methionine

Amino acid transporter

Brain, head and neck, lung and breast cancer, lymphomas

Choline

Choline kinase

Brain tumours, prostate, lung and esophageal cancer

Thymidine

Thymidine kinase-1

Tumour proliferation

Palmitate

Myocardinal tissue fatty acid metabolism

Heart diseases






Synthra C-11 Choline

Production of C-11 Choline and C-11 Methionine
Examples for [11C] compounds

[11C]-Radiotracer
Target
Application
Methionine Amino acid transporter Brain, head and neck, lung and breast cancer, lymphomas
Choline Choline kinase Brain tumors, prostate, lung and esophageal cancer


 


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